Top Big Cap Positive News Movers Premarket:

WVE: +18% Positive Data from FORWARD-53 Clinical Trial in DMD Including Significant Functional Benefit and Reversal of Muscle Damage after 48 Weeks of Dosing with WVE-N531

GME: +12% Earnings 

CHWY: +4% Earnings 

SMMT: +4% Upgraded to BUY @ Citi 

CTAS: +4% Earnings 

DLTR: +2% Earnings